BDBM202809 US10245267, Example 156::US10709712, Example 235::US9242969, 156::US9694016, 235

SMILES CCOc1ncc(cc1N1CCOCC1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=LSEPPTJNAQFEES-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202809   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
Affinity DataIC50:  2.48nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent